Discussion: Three factors determine the objective severity of pain, including in fibromyalgia patients.

The pains experienced by fibromyalgia patients reflect persistent damage (inflammation) in internal tissues with a relatively slow regenerative capacity. Over time, inflammation impairs blood flow and lymph fluid in the affected areas, making healing challenging.

1 The sensory nerves (nociceptors) density differs in different body areas. The head area, palms, hands, genitals, and nipples are rich in sensory nerves, which tend to hurt more.
Essential organs such as the brain and the liver are not pain-sensitive.

2 The intensity of tissue damage Volume correlates to the pain duration and scale.
Severe and prolonged tissue damage is more painful and lasts longer.

3 The Regeneration rate of the damaged tissue is directly proportional to the speed at which the pain passes. For example, skin cells recover quickly, so the pain passes relatively quickly when we cut ourselves superficially with a knife.


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