Discussion: The most appropriate timing for liver and gallbladder flushes.

For the first time performing a liver flush, I recommend starting with half the grapefruit mixture and olive oil. (You will have only 3/4 - 1 cup of the mixture instead of 1.5 - 2 cups.) You can use the regular double quantities if there are no significant side effects (like high fever). The best timing to perform a liver flush is on the weekend. Doing it on the weekend is wise because you may have a slight fever the day after or feel tired.

Link: Liver and Gallbladder flush. Instructions, Benefits, and Risks.
https://www.sf-healing.com/page/132 (Copy & Paste)